Parameter | Presentation | 2 years later | 2.5 years later | 3 years later |
---|---|---|---|---|
Spirometry | ||||
FEV1, L (% predicted) | 2.80 (110%) | 2.89 (113%) | 2.78 (108%) | 2.76 (109%) |
FVC, L (% predicted) | 3.70 (112%) | 3.71 (118%) | 3.39 (108%) | 3.53 (113%) |
FEV1/FVC, % | 78 | 78 | 82 | 78 |
PEF, L/sec (% predicted) | 6.35 (107%) | 6.65 (113%) | – | 7.09 (121%) |
Lung volumes | ||||
VC, L (% predicted) | 3.75 (114%) | 3.93 (121%) | – | 3.65 (113%) |
TLC, L (% predicted) | 5.20 (102%) | 4.94 (95%) | 4.90 (93%) | 5.06 (97%) |
RV, L (% predicted) | 1.45 (77%) | 1.01 (51%) | – | 1.41 (70%) |
Diffusion capacity | ||||
DLCO, mL/mm Hg/min (% predicted) *uncorrected for hemoglobin | 15.1 (67%) | 15.0 (68%) | 12.6 (57%) | 18.8 (85%) |
O2 sat (room air), % | 96 | 96 | 98 | 97 |
Note: DLCO = diffusing capacity of the lung for carbon monoxide, FEV1 = forced expiratory volume in 1 second, FEV1/FVC = ratio of FEV1 to FVC, FVC = forced vital capacity, O2 sat = oxygen saturation, PEF = peak expiratory flow, RV = residual volume, TLC = total lung capacity, VC = vital capacity.