[HTML][HTML] Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories

…, RA Kozak, M Krajden, T Kuschak, ALS Lang… - Journal of Clinical …, 2020 - Elsevier
With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential.
This study compared laboratory-developed tests (LDTs) used for the detection of SARS-CoV-…

[HTML][HTML] Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A …

…, A Ambrose, TF Hatchette, ALS Lang… - Vaccine, 2019 - Elsevier
Background The 13-valent pneumococcal conjugate vaccine (PCV13) was recently shown to
be effective against PCV13-type invasive pneumococcal disease (IPD) and pneumococcal …

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015

…, A Ambrose, TF Hatchette, ALS Lang… - BMJ open …, 2020 - bmjopenrespres.bmj.com
Background In Canada, 13-valent pneumococcal conjugate vaccine (PCV13) is recommended
in childhood, in individuals at high risk of invasive pneumococcal disease (IPD) and in …

[HTML][HTML] Recalibrated estimates of non-bacteremic and bacteremic pneumococcal community acquired pneumonia in hospitalized Canadian adults from 2010 to 2017 …

…, A Ambrose, TF Hatchette, ALS Lang… - Vaccine, 2022 - Elsevier
Objective(s) In the context of age- and risk-based pneumococcal vaccine recommendations
in Canada, this study presents updated data from active surveillance of pneumococcal …

Detection and prediction of Streptococcus pneumoniae serotypes directly from nasopharyngeal swabs using PCR

ALS Lang, SA McNeil, TF Hatchette… - Journal of Medical …, 2015 - microbiologyresearch.org
Monitoring Streptococcus pneumoniae serotype distribution is important to assess the impact
and effectiveness of pneumococcal vaccine programs. With the challenges of Quellung …

The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023

…, D Hinshaw, P Jha, JN Kanji, VA Kirsh, ALS Lang… - CMAJ, 2023 - Can Med Assoc
Amanda Lang reports receiving funding from the CITF, in support of the present manuscript,
for assay reagents and technologist salary. Dr. Lang has also received support from the …

Assessing the diagnostic accuracy of PCR-based detection of Streptococcus pneumoniae from nasopharyngeal swabs collected for viral studies in Canadian adults …

HD Gillis, ALS Lang, M ElSherif, I Martin… - BMJ open, 2017 - bmjopen.bmj.com
Study design Detection and serotyping of Streptococcus pneumoniae are important to assess
the impact of pneumococcal vaccines. This study describes the diagnostic accuracy of PCR…

Detection and differentiation of herpes simplex viruses by use of the viper platform: advantages, limitations, and concerns

ALS Lang, C Roberts, T Mazzulli… - Journal of Clinical …, 2014 - Am Soc Microbiol
The Viper HSV-Q x assay was evaluated for the detection of herpes simplex virus 1 (HSV-1)
and HSV-2 in specimens from oral, anogenital, and other miscellaneous sites. The HSV-Q x …

COVID-19 outbreak among physicians at a Canadian curling bonspiel: a descriptive observational study

…, CI Fung, AKH Woo, K Fonseca, ALS Lang… - … Open Access Journal, 2021 - cmajopen.ca
Background: Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is known to occur among individuals who congregate in large groups, especially during …

PCR-based discrimination of emerging Streptococcus pneumoniae serotypes 22F and 33F

…, A Griffith, I Martin, M Warhuus, ALS Lang… - Journal of …, 2018 - Elsevier
Serotyping of Streptococcus pneumoniae is important to monitor disease epidemiology and
assess the impact of pneumococcal vaccines. Traditionally, the Quellung reaction used …