X-chromosome inactivation results in the cis-limited dosage compensation of genes on one
of the pair of X chromosomes in mammalian females. Although most X-linked genes are …

X-CHROMOSOME inactivation results in the strictly cis-limited inactivation of many but not
all genes on one of the two X chromosomes during early development in somatic cells of …

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel …

X chromosome inactivation in mammalian females results in the cis-limited transcriptional
inactivity of most of the genes on one X chromosome. The X/ST gene is unique among X-…

Kallmann's syndrome (clinically characterized by hypogonadotropic hypogonadism and
inability to smell) is caused by a defect in the migration of olfactory neurons, and neurons …

Segmental copy-number variations (CNVs) in the human genome are associated with
developmental disorders and susceptibility to diseases. More importantly, CNVs may represent a …

The gene for the androgen receptor, mutations at which cause the X-linked androgen
insensitivity syndrome, has been localized to the q11----q12 region of the human X chromosome …

We have characterized the relationships between the design of cationic liposomes as a gene
transfer vehicle, their resulting biodistribution and processing in animals, and the level and …

Background Measurement of genome-wide DNA methylation (DNAm) has become an important
avenue for investigating potential physiologically-relevant epigenetic changes. Illumina …

Once thought to be a part of the ‘dark matter’ of the genome, long non-coding RNAs (lncRNAs)
are emerging as an integral functional component of the mammalian transcriptome. …