Benzodiazepines promote the binding of γ-aminobutyric acid (GABA) to its receptor. The “Z”
drugs (zopiclone, zaleplon and zolpidem) act in a similar manner. Flumazenil is a …

Flumazenil is a specific antagonist of the benzodiazepine (BZD) site associated with the
gamma aminobutyric (GABA) type A supramolecular receptor complex. This drug was …

The worldwide expansion in the use of benzodiazepines has led to their frequent, and often
inappropriate, use and to an increase in their involvement in self-induced poisoning and …

Abstract Flumazenil (RO 15-1788) was used to treat benzodiazepine (BZD) withdrawal after
abrupt cessation of chronic abuse of high-dose flunitrazepam or lormetazepam. Thirty-six …

Flumazenil, the first specific benzodiazepine (BZD) antagonist, is one of the most innovative
drugs to become available within the last few years. Flumazenil is indicated for the reversal …

The benzodiazepine antagonist flumazenil is a very valuable tool in the diagnosis and
treatment of intoxications in which benzodiazepines are involved. In case of a positive …

Globally benzodiazepines remain one of the most prescribed medication groups, especially
in the primary care setting. With such high levels of prescribing it is not surprising that …

Introduction Although not a potentially life-threatening poisoning, benzodiazepine (BZD)
intoxication may be life-threatening in special situations/populations or those with …

Flumazenil, a specific benzodiazepine (BZ) antagonist, has been used in our department for
treatment of some emergency cases. We treated different groups of comatose patients …

In anaesthesia and in the intensive care unit, benzodiazepines have proven safe and
effective agents for the induction and maintenance of sedation for a variety of therapeutic …