The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor

…, B Michalski, S Mathew, A Colquhoun… - Journal of …, 2004 - Wiley Online Library
Nerve growth factor (NGF) promotes neuronal survival and differentiation and stimulates
neurite outgrowth. NGF is synthesized as a precursor, proNGF, which undergoes post‐…

Cancer incidence in indigenous people in Australia, New Zealand, Canada, and the USA: a comparative population-based study

SP Moore, S Antoni, A Colquhoun, B Healy… - The Lancet …, 2015 - thelancet.com
Introduction Indigenous people have disproportionally worse health and lower life
expectancy than their non-indigenous counterparts in high-income countries. Cancer data for …

[HTML][HTML] First Nations emergency care in Alberta: descriptive results of a retrospective cohort study

…, C Barnabe, BR Holroyd, A Colquhoun… - BMC Health Services …, 2021 - Springer
Background Worse health outcomes are consistently reported for First Nations people in
Canada. Social, political and economic inequities as well as inequities in health care are major …

Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7-(benzolylamino)-4, 9-dihydro-4-methyl-9-oxo-pyrazolo [5, 1-b] quinazoline-2-carboxylic …

A Colquhoun, GM Lawrance, IL Shamovsky… - … of Pharmacology and …, 2004 - ASPET
The neurotrophin nerve growth factor (NGF) binds to two receptor types: the tyrosine kinase
receptor TrkA and the common neurotrophin receptor p75 NTR . Although many of the …

[HTML][HTML] Barriers and supports for uptake of human papillomavirus vaccination in indigenous people globally: a systematic review

…, C Barnabe, JR Guichon, A Colquhoun… - PLOS Global Public …, 2023 - journals.plos.org
Despite the availability of effective and safe human papillomavirus (HPV) vaccines that
reduce the incidence and impact of cervical cancer and other cancers, HPV vaccine coverage …

[HTML][HTML] Burden of disease from Helicobacter pylori infection in western Canadian Arctic communities

…, HJ Chang, L McAlpine, E Walker, A Colquhoun… - BMC Public Health, 2019 - Springer
Background Indigenous communities across the circumpolar north have elevated H. pylori (Hp)
prevalence and stomach cancer incidence. We aimed to describe the Hp-associated …

Obesity and the incidence of upper gastrointestinal cancers: an ecological approach to examine differences across age and sex

M Arnold, A Colquhoun, MB Cook, J Ferlay… - … Biomarkers & Prevention, 2016 - AACR
Background: Esophageal and gastric cancers differ in their epidemiology but have several
risk factors in common. The aim of this study was to assess age and sex differences in the …

[HTML][HTML] Barriers, supports, and effective interventions for uptake of human papillomavirus-and other vaccines within global and Canadian Indigenous peoples: a …

…, L Bill, B Healy, C Healy, J Guichon, A Colquhoun… - Systematic reviews, 2018 - Springer
Background Despite the existence of human papilloma virus (HPV) vaccines with demonstrated
safety and effectiveness and funded HPV vaccination programs, coverage rates are …

[HTML][HTML] Gastric cancer in northern Canadian populations: a focus on cardia and non-cardia subsites

A Colquhoun, H Hannah, A Corriveau, B Hanley… - Cancers, 2019 - mdpi.com
In northern Canada where there is a high prevalence of Helicobacter pylori infection, there
is a paucity of information on gastric cancer by the topographical subsites cardia (CGC) and …

[PDF][PDF] An investigation of cancer incidence in a First Nations community in Alberta, Canada, 1995-2006

A Colquhoun, Z Jiang, G Maiangowi… - Health Promotion and …, 2010 - researchgate.net
1. Surveillance and Health Status Assessment, Population and Public Health–Alberta
Health Services, Edmonton, Alberta 2. Aboriginal Health, Population and Public Health–Alberta …